829-3 Early results from the Japanese asparagus trial
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Everolimus and Early Calcineurin Inhibitor Withdrawal: 3-Year Results From a Randomized Trial in Liver Transplantation
The feasibility of de novo everolimus without calcineurin inhibitor (CNI) therapy following liver transplantation was assessed in a multicenter, prospective, open-label trial. Liver transplant patients were randomized at 4 weeks to start everolimus and discontinue CNI, or continue their current CNI-based regimen. The primary endpoint was adjusted estimated GFR (eGFR; Cockcroft-Gault) at month 1...
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Crohn’s disease (CD) is associated with delayed neutrophil recruitment and bacterial clearance at sites of acute inflammation as a result of impaired secretion of proinflammatory cytokines by macrophages. To investigate the impaired cytokine secretion and confirmour previous findings, weperformed transcriptomic analysis in macrophages and identified a subgroup of individuals with CD who had low...
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In the injured central nervous system (CNS), reactive astrocytes form a glial scar and are considered to be detrimental for axonal regeneration, but their function remains elusive. Here we show that reactive astrocytes have a crucial role in wound healing and functional recovery by using mice with a selective deletion of the protein signal transducer and activator of transcription 3 (Stat3) or ...
متن کامل829 Young.qxd
Recruitment and retention of general practitioners (GPs) has become an issue of major concern in recent years. However, much of the evidence is anecdotal and some commentators continue to question the scale of workforce problems. Hence, there is a need to establish a clear picture of those instabilities (i.e. imbalances between demand and supply) that do exist in the GP labour market in the UK....
متن کاملImmediate vs. early loading of dental implants: 3-year results of a randomized controlled clinical trial.
OBJECTIVES The aim of the present study was to test whether or not immediately loaded implants exhibit the same survival rates as early loaded implants. MATERIAL AND METHODS Eleven patients with bilateral free end mandibles were randomly assigned to treatment either with immediately (test) or early loaded implants (control). Test implants received provisionals in occlusion on the day of surge...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2004
ISSN: 0735-1097
DOI: 10.1016/s0735-1097(04)91208-9